Kidney Stones >; Tamsulosin Ineffective for Small Ureteral Stones In the double-blind STONE (Study of Tamsulosin for Urolithiasis in the. Nephrolithiasis specifically refers to calculi in the kidneys, but renal selective blockers, such as tamsulosin, also relax the musculature of the. Medscape – Benign prostatic hyperplasia-specific dosing for Flomax (tamsulosin), frequency-based adverse effects, comprehensive interactions.

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The Use of Alpha-Blockers for the Treatment of Nephrolithiasis

If you have any questions about the drugs you are taking, check with your f,omax, nurse or pharmacist. They believe, however, tamsulosin should still be considered for ureteral stones larger than 5 mm in diameter based on other research and the small mean stone size in the current study 3. Both tamsulosin and nifedipine significantly increased stone passage rates. Both the mean general health index score and mean sexual matters score were significantly better in patients taking alfuzosin.

They enrolled 96 patients with distal ureteral stones smaller than 10 mm. Interestingly, they found that in 4 patients receiving phentolamine, their renal obstruction was vlomax, as depicted by intravenous pyelography, as was their pain.

The narrator then refers to a couple smaller studies done in and then one in Once we make a diagnosis, our primary goal in the ED is pain relief. Leave Us a Review. In the absence of robust or even decent evidence, we should not be using this medication for ED patients presenting with renal colic. Applicability to our patients in the ED is unclear.


Resim and colleagues 19 studied 60 patients with lower ureteral stones who were divided into 2 groups, 1 of which received tenoxicam, an NSAID, and another group that received tamsulosin in addition to tenoxicam. Ureteral stents are often used in the treatment of renal and ureteral stones. The idea of medical expulsion therapy seems to have entered the EM realm after the publication of a systematic review in Annals of Emergency Medicine in This significant bias again renders the data non-helpful.

September 22, at 5: August 7, Renal colic is a common ED presentation. Main Points Medical expulsion therapy is a useful adjunct to observation in the conservative management of ureteral stones.

Patients receiving tamsulosin required significantly fewer injections of diclofenac, 0.

Tamsulosin Ineffective for Small Ureteral Stones – Renal and Urology News

Yilmaz E neprholithiasis al EM by Salim R. Ferre RM et al. Post Peer Reviewed By: Related Topics Urologic Disorders. Feel free to contribute!

Lee SW et al. Hollingsworth JM et al. I strongly disagree with the final statement from your urology group.

Distal ureteric stones and tamsulosin: You can browse Drugs A-Z for f,omax specific prescription or over-the-counter drug or look up drugs based on your specific condition.


The investigators concluded that tamsulosin could improve stone-free rates after SWL of distal ureteral stones with minimal side effects. Patients discharged on parenteral diclofenac not standard care for us This is the only randomized trial to show a benefit to tamsulosin but there are some major issues. Arch Intern Med ; Porpiglia F et al Patients aged 18 to 65 with a ureteric stone confirmed by non-contrast computed tomography of the kidney, ureter and bladder will be randomized to receive nifedipine, tamsulosin or placebo participants per arm for a maximum of 28 days.

This study adds to the nephrolithiasix, high-quality evidence that tamsulosin offers no significant benefit and further challenges current practices. Is there a role for alpha1-blockers in treating double-J stent-related symptoms?

Non-blinding design would favor drug but no benefit anyway. Arch Int Med For the study, patients could have stones in any part of the ureter. Ann of EM ; Speedy elimination of ureterolithiasis in lower part of ureters with the alpha 1-blocker tamsulosin.

It appears this study was not on an ED population as well. The narrator holds this study as exemplary and uses it to question the blanket use of Tamsulosin in medical expulsion therapy.

For over a decade, calcium channel blockers i.